The effect of external sodium concentration on the sodium fluxes in frog skeletal muscle
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چکیده
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Strophanthidin-sensitive sodium fluxes in metabolically poisoned frog skeletal muscle
Strophanthidin-sensitive and insensitive unidirectional fluxes of Na were measured in fog sartorius muscles whose internal Na levels were elevated by overnight storage in the cold. ATP levels were lowered, and ADP levels raised, by metabolic poisoning with either 2,4-dinitrofluorobenzene or iodoacetamide. Strophanthidin-sensitive Na efflux and influx both increased after poisoning, while stroph...
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Effects of External Potassium and Strophanthidin on Sodium Fluxes in Frog Striated Muscle
Unidirectional Na fluxes in isolated fibers from the frog's semitendinosus muscle were measured in the presence of strophanthidin and increased external potassium ion concentrations. Strophanthidin at a concentration of 10(-5)M inhibited about 80 per cent of the resting Na efflux without having any detectable effect on the resting Na influx. From this it is concluded that the major portion of t...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1959
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1959.sp006264